by Clinical Neuropsychologist Online | Wednesday, May 1, 2024 | Neuro Podcasts
In this episode, we discuss various aspects of delirium with Dr. Kirk Stucky. Topics covered include definitions and terminology, prevalence, risk factors, functional reserve, hypoactive and hyperactive presentations, pathophysiology, differential diagnosis with...
by Clinical Neuropsychologist Online | Wednesday, May 1, 2024 | Dementia
Abstract This article describes the public health impact of Alzheimer’s disease (AD), including prevalence and incidence, mortality and morbidity, use and costs of care and the ramifications of AD for family caregivers, the dementia workforce and society. The...
by Clinical Neuropsychologist Online | Wednesday, May 1, 2024 | Neuroscience
Nature Neuroscience, Published online: 01 May 2024; doi:10.1038/s41593-024-01633-3This paper shows that compulsive-like grooming in Sapap3-knockout mice can be reduced by closed-loop optogenetic stimulation of striatal interneurons based on grooming onset prediction,...
by Clinical Neuropsychologist Online | Tuesday, April 30, 2024 | Dementia
Abstract INTRODUCTION Genome-wide association studies have identified over 70 genetic loci associated with late-onset Alzheimer’s disease (LOAD), but few candidate polymorphisms have been functionally assessed for disease relevance and mechanism of action....
by Clinical Neuropsychologist Online | Tuesday, April 30, 2024 | Dementia
Abstract Experimental laboratory research has an important role to play in dementia prevention. Mechanisms underlying modifiable risk factors for dementia are promising targets for dementia prevention but are difficult to investigate in human populations due to...