by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Neuroscience
Nature Neuroscience, Published online: 22 February 2024; doi:10.1038/s41593-024-01572-zBrain connections modulated by 534 deep-brain-stimulation electrodes revealed a gradient of circuits involved in dystonia, Parkinson’s disease, Tourette’s syndrome and...
by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Dementia
Abstract INTRODUCTION Verbal fluency tasks are common in Alzheimer’s disease (AD) assessments. Yet, standard valid response counts fail to reveal disease-specific semantic memory patterns. Here, we leveraged automated word-property analysis to capture...
by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Dementia
Abstract INTRODUCTION The results of the CLARITY-AD, GRADUATE I and II, and TRAILBLAZER-ALZ 2 trials have rekindled discussion on the impact of amyloid-targeting drugs. We use a Bayesian approach to quantify how rational observers would have updated their prior...
by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Dementia
Abstract INTRODUCTION We investigated whether retinal capillary perfusion is a biomarker of cerebral small vessel disease and impaired cognition among Black Americans, an understudied group at higher risk for dementia. METHODS We enrolled 96 Black Americans without...
by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Dementia
Abstract INTRODUCTION Evidence is limited on the role of mid-life Dietary Approaches to Stop Hypertension (DASH) diet in late-life subjective cognitive complaints (SCCs). METHODS We included 5116 women (mean age in 1985–1991: 46 years) from the New York University...