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cGAS-mediated type I IFN signaling contributes to disease progression in drug-refractory epilepsy

by Clinical Neuropsychologist Online | Wednesday, July 29, 2026 | Neuroscience

Nature Neuroscience, Published online: 29 July 2026; doi:10.1038/s41593-026-02384-zHuang et al. found that stressed neurons release DNA that activates the immune sensor cGAS, driving inflammatory responses that worsen seizures and mortality in Dravet syndrome....

Mitochondrial accumulation and lysosomal dysfunction result in mitochondrial plaques in Alzheimer’s disease

by Clinical Neuropsychologist Online | Wednesday, July 29, 2026 | Neuroscience

Nature Neuroscience, Published online: 29 July 2026; doi:10.1038/s41593-026-02390-1Researchers identify mitochondrial plaques, a previously unrecognized and highly acidic mitochondria-based pathological structure in Alzheimer’s disease, and demonstrate that they...

Experience reorganizes content-specific memory traces in macaques

by Clinical Neuropsychologist Online | Wednesday, July 29, 2026 | Neuroscience

Nature Neuroscience, Published online: 29 July 2026; doi:10.1038/s41593-026-02357-2In macaques, old memories, relative to new ones, are supported by more stable and interconnected cell assemblies. New-biased and old-biased assemblies reactivate during overnight sleep...

Evidence of stage‐specific cognitive reserve effects on longitudinal cognition in amyotrophic lateral sclerosis

by Clinical Neuropsychologist Online | Wednesday, July 29, 2026 | Neuropsychology (general)

Abstract About 50% of amyotrophic lateral sclerosis (ALS) patients develop cognitive-behavioural impairment, yet longitudinal studies diverge on onset and extent of decline. Cognitive reserve (CR) may modulate cognitive trajectories, although longitudinal evidence...

Refining our understanding of sleep impairment and connection to Alzheimer’s disease in preclinical models

by Clinical Neuropsychologist Online | Tuesday, July 28, 2026 | Dementia

Alzheimer’s &Dementia, Volume 22, Issue 8, August 2026. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: | July 28, 2026 Neuro-Dementia Previous...
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