Gray matter volume mediates the association of long‐term blood pressure variability with cognitive function in an adult population

by Clinical Neuropsychologist | Friday, June 14, 2024 | Dementia

Abstract INTRODUCTION We delineated the associations among long-term blood pressure variability (BPV), brain structure, and cognitive function. METHODS We included 1254 adult participants from the Kailuan study. BPV was calculated from 2006 to 2020. Brain magnetic...

Remote and unsupervised digital memory assessments can reliably detect cognitive impairment in Alzheimer’s disease

by Clinical Neuropsychologist | Thursday, June 13, 2024 | Dementia

Abstract INTRODUCTION Remote unsupervised cognitive assessments have the potential to complement and facilitate cognitive assessment in clinical and research settings. METHODS Here, we evaluate the usability, validity, and reliability of unsupervised remote memory...

Non‐hemorrhagic imaging markers of cerebral amyloid angiopathy in memory clinic patients

by Clinical Neuropsychologist | Thursday, June 13, 2024 | Dementia

Abstract INTRODUCTION The Boston criteria v2.0 for cerebral amyloid angiopathy (CAA) incorporated non-hemorrhagic imaging markers. Their prevalence and significance in patients with cognitive impairment remain uncertain. METHODS We studied 622 memory clinic patients...

How are early‐career dementia researchers considered and supported on a national level by dementia plans and organizations? An overview of global policy approaches

by Clinical Neuropsychologist | Thursday, June 13, 2024 | Dementia

Abstract INTRODUCTION Despite representing an essential workforce, it is unclear how global policy efforts target early-career dementia researchers (ECDRs). Thus, this study aimed to provide an overview of policies through which ECDRs are considered and supported by...

Concurrent nutrient deficiencies are associated with dementia incidence

by Clinical Neuropsychologist | Thursday, June 13, 2024 | Dementia

Abstract INTRODUCTION While observational research suggests a protective role for nutrition in brain aging, intervention studies remain inconclusive. This failing translation from observational to interventional research may result from overlooking nutrient...

Neurofilaments and progranulin are related to atrophy in frontotemporal lobar degeneration – A transdiagnostic study cross‐validating atrophy and fluid biomarkers

by Clinical Neuropsychologist | Thursday, June 13, 2024 | Dementia

Abstract INTRODUCTION Frontotemporal lobar degeneration (FTLD) encompasses behavioral variant frontotemporal dementia (bvFTD), progressive supranuclear palsy, corticobasal syndrome/degeneration, and primary progressive aphasias (PPAs). We cross-validated fluid...