by Clinical Neuropsychologist | Thursday, March 20, 2025 | Dementia
Abstract INTRODUCTION Accelerated long-term forgetting (LTF) might be an early marker of subtle memory changes in older adults at risk for Alzheimer’s disease (AD). We leveraged remote, multi-day digital testing to characterize LTF in older adults and...
by Clinical Neuropsychologist | Thursday, March 20, 2025 | Dementia
Abstract INTRODUCTION Alzheimer’s disease (AD) is characterized by amyloid pathology and neuroinflammation, leading to cognitive decline. Targeting histone deacetylase-11 (HDAC11) offers a novel therapeutic strategy due to its role in immune regulation. METHODS...
by Clinical Neuropsychologist | Thursday, March 20, 2025 | Dementia
Abstract Interventions addressing modifiable personal and environmental factors are critical to optimize dementia mealtime care, caregiving, and outcomes. This review synthesized the characteristics and effects of non-pharmacological interventions on mealtime care and...
by Clinical Neuropsychologist | Thursday, March 20, 2025 | Dementia
Abstract INTRODUCTION Plasma biomarkers sensitive to Alzheimer’s disease (AD) proteinopathy prior to the onset of dementia have significant implications for early detection. METHODS In 304 individuals without dementia, we investigated whether C2N Diagnostics’...
by Clinical Neuropsychologist | Friday, March 14, 2025 | Dementia
Abstract INTRODUCTION Digital voice analysis is an emerging tool for differentiating cognitive states, but it poses privacy risks as automated systems may inadvertently identify speakers. METHODS We developed a computational framework to evaluate the trade-off between...
by Clinical Neuropsychologist | Thursday, March 13, 2025 | Dementia
Dementia, Ahead of Print. Improving supports to enhance wellbeing of people living with dementia is a priority. Engaging people living with dementia, care partners, and other stakeholders in development of interventions increases the likelihood they will be relevant...
