Early‐onset dementia and risk of hip fracture and major osteoporotic fractures

by Clinical Neuropsychologist Online | Tuesday, April 2, 2024 | Dementia

Abstract INTRODUCTION There is limited knowledge about early-onset dementia (EOD) on fracture risk. METHODS Individuals ages 50 to 64 were identified from the National Database of Health Insurance Claims and Specific Health Checkups of Japan (2012 to 2019). The...

The ABC’s of Alzheimer risk gene ABCA7

by Clinical Neuropsychologist Online | Monday, April 1, 2024 | Dementia

Abstract Alzheimer’s disease (AD) is a growing problem worldwide. Since ABCA7’s identification as a risk gene, it has been extensively researched for its role in the disease. We review its recently characterized structure and what the mechanistic insights teach...

The six brain‐specific TAU isoforms and their role in Alzheimer’s disease and related neurodegenerative dementia syndromes

by Clinical Neuropsychologist Online | Monday, April 1, 2024 | Dementia

Abstract INTRODUCTION Alternative splicing of the human MAPT gene generates six brain-specific TAU isoforms. Imbalances in the TAU isoform ratio can lead to neurodegenerative diseases, underscoring the need for precise control over TAU isoform balance. Tauopathies,...

Correction to the role of Apolipoprotein E4 allele in the gut microbiome of Puerto Ricans with Alzheimer’s disease

by Clinical Neuropsychologist Online | Saturday, March 30, 2024 | Dementia

Alzheimer’s &Dementia, EarlyView. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: | March 30, 2024 Wiley: Alzheimer’s & Dementia: Table...

Histories of neighborhood socioeconomic status contribute to race differences in later‐life cognition

by Clinical Neuropsychologist Online | Saturday, March 30, 2024 | Dementia

Abstract INTRODUCTION Neighborhood characteristics are increasingly implicated in cognitive health disparities, but no research has investigated how the historical context of neighborhoods shapes these disparities. METHODS Four hundred sixty-four Black (55%) and White...

Meaningful co-production to bring meaningful change: Developing the Allied Health Professionals Dementia Framework for Wales together

by Clinical Neuropsychologist Online | Thursday, March 28, 2024 | Dementia

Dementia, Volume 23, Issue 5, Page 724-740, July 2024. In line with increasing participatory approaches to service and research design, there is a growing appreciation of the need to understand the lived experience of people accessing care and support, including...