by Clinical Neuropsychologist | Friday, January 3, 2025 | Dementia
Abstract Understanding the physiological connection between platelets and brain function reveals new paradigms in neurodegenerative disease treatment. Platelets, traditionally associated with hemostasis, but also sometimes regarded as a mirror of neurons in the blood...
by Clinical Neuropsychologist | Friday, January 3, 2025 | Dementia
Abstract Background Despite significant advancements in the development of blood biomarkers for AD, challenges persist due to the complex interplay of genetic and environmental risk factors in AD pathogenesis. Epigenetic processes, including non-coding RNAs and...
by Clinical Neuropsychologist | Thursday, January 2, 2025 | Dementia
Abstract INTRODUCTION Whole genome methylation sequencing (WGMS) in blood identifies differential DNA methylation in persons with late-onset dementia due to Alzheimer’s disease (AD) but has not been tested in persons with mild cognitive impairment (MCI). METHODS...
by Clinical Neuropsychologist | Wednesday, January 1, 2025 | Dementia
Alzheimer’s &Dementia, EarlyView. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: | January 1, 2025 Wiley: Alzheimer’s & Dementia:...
by Clinical Neuropsychologist | Tuesday, December 31, 2024 | Dementia
Abstract INTRODUCTION Alzheimer’s disease (AD), primary age-related tauopathy (PART), and chronic traumatic encephalopathy (CTE) all feature hyperphosphorylated tau (p-tau)–immunoreactive neurofibrillary degeneration, but differ in neuroanatomical distribution...
by Clinical Neuropsychologist | Tuesday, December 31, 2024 | Dementia
Abstract INTRODUCTION Some individuals show intact cognition despite the presence of neuropathological hallmarks of Alzheimer’s disease (AD). The plasticity of parvalbumin (PV)-containing interneurons might contribute to resilience. Perineuronal nets (PNNs),...