by Clinical Neuropsychologist | Thursday, September 12, 2024 | Dementia
Abstract INTRODUCTION Regional glucose hypometabolism resulting in glutamate loss has been shown as one of the characteristics of Alzheimer’s disease (AD). Because the impact of AD varies between the sexes, we utilized glutamate-weighted chemical exchange...
by Clinical Neuropsychologist | Wednesday, September 11, 2024 | Dementia
Abstract INTRODUCTION We examined the relations of misfolded alpha synuclein (α-synuclein) with Alzheimer’s disease (AD) biomarkers in two large independent cohorts. METHODS We included Biomarkers for Identifying Neurodegenerative Disorders Early and Reliably...
by Clinical Neuropsychologist | Wednesday, September 11, 2024 | Dementia
Abstract INTRODUCTION Word-list recall tests are routinely used for cognitive assessment, and process scoring may improve their accuracy. We examined whether Alzheimer’s Disease Assessment Scale–Cognitive subscale (ADAS-Cog) derived, process-based digital...
by Clinical Neuropsychologist | Wednesday, September 11, 2024 | Dementia
Abstract The magnetic resonance imaging (MRI) Core has been operating since Alzheimer’s Disease Neuroimaging Initiative’s (ADNI) inception, providing 20 years of data including reliable, multi-platform standardized protocols, carefully curated image data,...
by Clinical Neuropsychologist | Tuesday, September 10, 2024 | Dementia
Abstract INTRODUCTION Frontotemporal dementia (FTD) is characterized by phenotypic and genetic heterogeneities. However, reports on the large Chinese FTD cohort are lacking. METHODS Two hundred forty-eight patients with FTD were enrolled. All patients and 2010 healthy...
by Clinical Neuropsychologist | Tuesday, September 10, 2024 | Dementia
Abstract INTRODUCTION Few studies have examined the relationship between education and cognition among the oldest–old. METHODS Cognitive assessments were conducted biannually for 803 participants (62.6% women) of LifeAfter90, a longitudinal study of individuals ≥ 90...
