by Clinical Neuropsychologist | Wednesday, September 4, 2024 | Dementia
Abstract BACKGROUND The number of people with dementia is increasing in Japan, and establishing evidence for preventing dementia is necessary. METHODS This study was a randomized controlled trial in cognitively normal community-dwelling older adults aged 65 to 85 with...
by Clinical Neuropsychologist | Wednesday, September 4, 2024 | Dementia
Abstract INTRODUCTION Dementia often involves comorbid Alzheimer’s and vascular pathology, but their combined impact warrants additional study. METHODS We analyzed the Systolic Blood Pressure Intervention Trial and categorized white matter hyperintensity (WMH)...
by Clinical Neuropsychologist | Monday, September 2, 2024 | Dementia
Abstract INTRODUCTION The relationship between cerebrovascular disease (CVD) and amyloid beta (Aβ) in Alzheimer’s disease (AD) is understudied. We hypothesized that magnetic resonance imaging (MRI)–based CVD biomarkers—including cerebral microbleeds (CMBs),...
by Clinical Neuropsychologist | Monday, September 2, 2024 | Dementia
Abstract INTRODUCTION We evaluated preliminary feasibility of a digital, culturally-informed approach to recruit and screen participants for the Alzheimer’s Disease Neuroimaging Initiative (ADNI4). METHODS Participants were recruited using digital advertising...
by Clinical Neuropsychologist | Monday, September 2, 2024 | Dementia
Abstract INTRODUCTION Brain network dynamics have been extensively explored in patients with amnestic mild cognitive impairment (aMCI); however, differences in single- and multiple-domain aMCI (SD-aMCI and MD-aMCI) remain unclear. METHODS Using multicenter datasets,...
by Clinical Neuropsychologist | Saturday, August 31, 2024 | Dementia
Abstract INTRODUCTION CD33 rs3865444 and hypertension (HTN) are related to cognitive impairment, individually. However, little is known about their combined effects on cognitive function in older adults. METHODS This population-based study included 4368 dementia-free...
