Beyond Parkinson’s Disease: A Narrative Review of Neuromelanin MRI in Neurodegenerative Diseases

by Clinical Neuropsychologist | Monday, December 1, 2025 | Neuroimaging

ABSTRACT Background and Purpose Neuromelanin-sensitive magnetic resonance imaging (NM-MRI) is an emerging noninvasive biomarker of catecholaminergic neurons. It assesses neuromelanin-rich regions such as the substantia nigra pars compacta (SNc) and locus coeruleus...

Neurodegeneration With Brain Iron Accumulation and Ferroptosis Disorders in Children and Adults: An Imaging Review

by Clinical Neuropsychologist | Monday, December 1, 2025 | Neuroimaging

ABSTRACT Neurodegeneration with brain iron accumulation (NBIA) refers to a group of rare genetic disorders characterized by abnormal iron deposition in the basal ganglia and brainstem due to impaired iron homeostasis. Disease severity and manifestations vary according...

Imaging Biomarkers in Idiopathic Normal Pressure Hydrocephalus: Associations With Symptoms and 1‐Year Treatment Outcomes

by Clinical Neuropsychologist | Saturday, November 29, 2025 | Neuroimaging

ABSTRACT Background and Purpose Idiopathic normal pressure hydrocephalus (iNPH) is a neurological disorder that primarily affects older adults and is typically characterized clinically by a triad of symptoms: gait disturbance, urinary urgency or incontinence, and...

New Stent Retriever Technology Versus Standard Devices for Anterior Large Vessel Thrombectomy: A Multicenter Study

by Clinical Neuropsychologist | Friday, November 28, 2025 | Neuroimaging

ABSTRACT Background and Purpose Guidelines recommend stent retrievers (SRs) for treating large vessel occlusion (LVO) stroke. We assessed noninferiority of the iNtercept (iVascular) SR with a self-expanding basket on a pusher wire versus contemporary SRs (CSRs) using...

The Effect of Gadolinium on Synthetic Magnetic Resonance Quantitative Imaging

by Clinical Neuropsychologist | Tuesday, November 18, 2025 | Neuroimaging

ABSTRACT Background and Purpose Synthetic (Sy) MRI is a clinically approved technique providing quantitative MRI measures based on T1-weighted, T2-weighted, and proton density relaxometry. MRI sequences are often acquired after contrast injection with gadolinium (Gd)...

Cerebral Perfusion and Blood−Brain Barrier Changes After Cranioplasty: A Diffusion‐Prepared Arterial Spin Labeling Study

by Clinical Neuropsychologist | Saturday, November 15, 2025 | Neuroimaging

ABSTRACT Background and Purpose Cranioplasty reconstruction after hemicraniectomy restores skull integrity and has been associated with neurological improvement, but the physiological mechanisms underlying recovery remain incompletely understood. This study...