Longitudinal Identification of Pre‐Lesional Tissue in Multiple Sclerosis With Advanced Diffusion MRI

by Clinical Neuropsychologist | Wednesday, February 12, 2025 | Neuroimaging

ABSTRACT Background and Purpose Structural MRI (sMRI) is used in monitoring multiple sclerosis (MS) but lacks sensitivity in detecting clinically relevant damage to normal-appearing white matter (NAWM), that is, pre-lesional tissue, and specificity for identifying the...

Subject‐Based Transfer Learning in Longitudinal Multiple Sclerosis Lesion Segmentation

by Clinical Neuropsychologist | Sunday, February 9, 2025 | Neuroimaging

ABSTRACT Background and Purpose Accurate and consistent lesion segmentation from magnetic resonance imaging is required for longitudinal multiple sclerosis (MS) data analysis. In this work, we propose two new transfer learning-based pipelines to improve segmentation...

Magnetization Transfer Ratio in the Typically Developing Pediatric Spinal Cord: Normative Data and Age Correlation

by Clinical Neuropsychologist | Sunday, February 9, 2025 | Neuroimaging

Abstract Background and Purpose This study presents automated atlas-based magnetization transfer (MT) measurements of the typically developing pediatric cervical spinal cord (SC). We report normative MT ratio (MTR) values from the whole cervical cord white matter (WM)...

Technical Considerations in the TCD Evaluation of Cerebral Circulatory Arrest in Death by Neurological Criteria

by Clinical Neuropsychologist | Saturday, February 8, 2025 | Neuroimaging

ABSTRACT Background and Purpose Ancillary testing is essential for diagnosing brain death/death by neurologic criteria (BD/DNC) when clinical determination (neurologic exam and apnea testing) cannot be fully or safely performed. Transcranial Doppler ultrasound (TCD)...

Grading Right‐to‐Left Shunt With Transforaminal Doppler: A Valid Approach in Patients With Cryptogenic Stroke

by Clinical Neuropsychologist | Thursday, February 6, 2025 | Neuroimaging

ABSTRACT Background and Purpose Right-to-left shunt (RLS), usually related to a patent foramen ovale (PFO), is an important cause of cryptogenic stroke (CS) in young patients. Transcranial Doppler (TCD) with an agitated saline bubble study is a highly sensitive...

Resting‐State Functional MRI Regional Homogeneity Correlates With Motor Scores in Parkinson’s Disease

by Clinical Neuropsychologist | Tuesday, February 4, 2025 | Neuroimaging

ABSTRACT Background and Purpose This study investigated the neural mechanisms underlying Parkinson’s disease (PD) subtypes—tremor dominant (TD) and postural instability gait difficulty (PIGD)—by analyzing regional homogeneity (ReHo) values from resting-state...