by Clinical Neuropsychologist Online | Friday, November 22, 2024 | Neuroscience
Nature Neuroscience, Published online: 22 November 2024; doi:10.1038/s41593-024-01811-3Launched in 2013, the BRAIN Initiative (BRAIN) in the United States aimed to unlock the mysteries of the brain and develop new treatments for neurological and neuropsychiatric...
by Clinical Neuropsychologist Online | Thursday, November 21, 2024 | Neuroscience
Nature Neuroscience, Published online: 21 November 2024; doi:10.1038/s41593-024-01812-2Here Zhang et al. establish multiscale relationships that link postmortem cell-type distributions with the in vivo functional organization of the human cerebral cortex, as assessed...
by Clinical Neuropsychologist Online | Thursday, November 21, 2024 | Neuroscience
Nature Neuroscience, Published online: 21 November 2024; doi:10.1038/s41593-024-01801-5Using cryo-electron tomography (cryo-ET) and proteomics, this study identifies the tethering of pathological tau filaments within defined brain extracellular vesicles in Alzheimer’s...
by Clinical Neuropsychologist Online | Thursday, November 21, 2024 | Neuroscience
Nature Neuroscience, Published online: 21 November 2024; doi:10.1038/s41593-024-01722-3The cerebral cortex shows complex organization across diverse biological scales, from regional chemical and cellular specializations to macroscale functional networks. Zhang et al....
by Clinical Neuropsychologist Online | Tuesday, November 19, 2024 | Neuroscience
Nature Neuroscience, Published online: 19 November 2024; doi:10.1038/s41593-024-01799-wJhang et al. identify a prefrontal–pontomedullary pathway that slows breathing and reduces anxiety in mice, where the pontine reticular nucleus converts excitatory prefrontal inputs...
by Clinical Neuropsychologist Online | Monday, November 18, 2024 | Neuroscience
Nature Neuroscience, Published online: 18 November 2024; doi:10.1038/s41593-024-01809-xThe CaMKII holoenzyme was long thought to mediate memory storage via an autophosphorylation reaction that occurs between its subunits at Thr286 (pThr286). This Perspective explains...