Flexible multitask computation in recurrent networks utilizes shared dynamical motifs

by Clinical Neuropsychologist Online | Tuesday, July 9, 2024 | Neuroscience

Nature Neuroscience, Published online: 09 July 2024; doi:10.1038/s41593-024-01668-6The authors identify reusable ‘dynamical motifs’ in artificial neural networks. These motifs enable flexible recombination of previously learned capabilities, promoting modular,...

Microglia are dispensable for experience-dependent refinement of mouse visual circuitry

by Clinical Neuropsychologist Online | Monday, July 8, 2024 | Neuroscience

Nature Neuroscience, Published online: 08 July 2024; doi:10.1038/s41593-024-01706-3The authors test the model that microglia are crucial for the developmental refinement of neural circuitry by depleting them with PLX5622. Microglia prove dispensable for the...

A vagal–brainstem interoceptive circuit for cough-like defensive behaviors in mice

by Clinical Neuropsychologist Online | Monday, July 8, 2024 | Neuroscience

Nature Neuroscience, Published online: 08 July 2024; doi:10.1038/s41593-024-01712-5Gannot et al. show that Tac1 neurons in the NTS mediate an airway–vagal–brain pathway that is crucial for coughing in mice. These neurons receive direct vagal sensory inputs and...

Sexually dimorphic oxytocin circuits drive intragroup social conflict and aggression in wild house mice

by Clinical Neuropsychologist Online | Friday, July 5, 2024 | Neuroscience

Nature Neuroscience, Published online: 05 July 2024; doi:10.1038/s41593-024-01685-5In nature, female mice, like males, display aggression and dominant hierarchy. This study in wild mice identifies oxytocin-expressing neurons as a hub governing these behaviors,...

Striatal projection neurons coexpressing dopamine D1 and D2 receptors modulate the motor function of D1- and D2-SPNs

by Clinical Neuropsychologist Online | Thursday, July 4, 2024 | Neuroscience

Nature Neuroscience, Published online: 04 July 2024; doi:10.1038/s41593-024-01694-4Bonnavion, Varin and colleagues show that striatal projection neurons that coexpress dopamine D1 and D2 receptors have unique physiological properties and serve as a crucial third...

Phospholipid Scramblase 1 Controls Efficient Neurotransmission and Synaptic Vesicle Retrieval at Cerebellar Synapses

by Clinical Neuropsychologist Online | Thursday, July 4, 2024 | Neuroscience

Phospholipids (PLs) are asymmetrically distributed at the plasma membrane. This asymmetric lipid distribution is transiently altered during calcium-regulated exocytosis, but the impact of this transient remodeling on presynaptic function is currently unknown. As...