Integrated analysis of molecular atlases unveils modules driving developmental cell subtype specification in the human cortex

by Clinical Neuropsychologist | Monday, April 21, 2025 | Neuroscience

Nature Neuroscience, Published online: 21 April 2025; doi:10.1038/s41593-025-01933-2Nano et al. introduce a pipeline to generate meta-atlases of the human brain from existing single-cell datasets and extract gene modules linked to cell fate specification. Perturbing...

Gene programs driving cortical neuron specifications

by Clinical Neuropsychologist | Monday, April 21, 2025 | Neuroscience

Nature Neuroscience, Published online: 21 April 2025; doi:10.1038/s41593-025-01934-1The cerebral cortex of the human brain is crucial and complex, and includes different subtypes of neuron that need to be specified during development. How this process is regulated is...

Functionally distinct GABAergic amacrine cell types regulate spatiotemporal encoding in the mouse retina

by Clinical Neuropsychologist | Tuesday, April 15, 2025 | Neuroscience

Nature Neuroscience, Published online: 15 April 2025; doi:10.1038/s41593-025-01935-0GABA is the primary inhibitory neurotransmitter in the central nervous system. Using two-photon GABA imaging, Matsumoto et al. reveal over 40 GABA neuron types in the mouse retina,...

How to Use Your Brain to Make Time Work for You

by Clinical Neuropsychologist | Monday, April 14, 2025 | Neuroscience

Have you ever noticed how time stretches endlessly during a tedious presentation yet passes quickly when you’;re engaged in something exciting? This isn’;t just a trick of the mind, but a process shaped by the brain, and new results show anterior cingulate cortex...

Hippocampal output suppresses orbitofrontal cortex schema cell formation

by Clinical Neuropsychologist | Monday, April 14, 2025 | Neuroscience

Nature Neuroscience, Published online: 14 April 2025; doi:10.1038/s41593-025-01928-zInactivation of the ventral subiculum does not change existing schema cells in the orbitofrontal cortex (OFC) but aids their formation during new learning. This challenges the idea...

Spatially clustered neurons in the bat midbrain encode vocalization categories

by Clinical Neuropsychologist | Monday, April 14, 2025 | Neuroscience

Nature Neuroscience, Published online: 14 April 2025; doi:10.1038/s41593-025-01932-3Using two-photon imaging in awake bats, the authors show that the inferior colliculus encodes vocalization categories as categorical primitives—spatially clustered, category-selective...