Dopamine-mediated formation of a memory module in the nucleus accumbens for goal-directed navigation

by Clinical Neuropsychologist | Friday, September 27, 2024 | Neuroscience

Nature Neuroscience, Published online: 27 September 2024; doi:10.1038/s41593-024-01770-9Jung et al. show that shelter experience boosts dopamine release in the nucleus accumbens, generating a goal-location memory. Reactivating a neuronal ensemble developed from...

Advances and controversies in meningeal biology

by Clinical Neuropsychologist | Friday, September 27, 2024 | Neuroscience

Nature Neuroscience, Published online: 27 September 2024; doi:10.1038/s41593-024-01701-8The authors review current knowledge of the molecular identity and functions of the dura, arachnoid and pial layers of meninges and controversial aspects of meningeal biology that...

How Threats Shape the Organization of our Memories

by Clinical Neuropsychologist | Thursday, September 26, 2024 | Neuroscience

Bad experiences can shape our lives in unconscious ways. If you, say, tried a new dish at a restaurant and got food poisoning, you may not only avoid that restaurant in the future but potentially that dish, even in other settings. Researchers have documented in many...

Single-cell m6A profiling in the mouse brain uncovers cell type-specific RNA methylomes and age-dependent differential methylation

by Clinical Neuropsychologist | Tuesday, September 24, 2024 | Neuroscience

Nature Neuroscience, Published online: 24 September 2024; doi:10.1038/s41593-024-01768-3The authors perform the first single-cell profiling of m6A in the mouse brain. They uncover relative hypomethylation of microglial mRNA compared to other cell types, and they...

A potential target for noninvasive neuromodulation of PTSD symptoms derived from focal brain lesions in veterans

by Clinical Neuropsychologist | Tuesday, September 24, 2024 | Neuroscience

Nature Neuroscience, Published online: 24 September 2024; doi:10.1038/s41593-024-01772-7Siddiqi et al. identified lesion locations that reduced probability of PTSD. These were connected to a brain circuit in which increased connectivity was associated with PTSD, thus...

Publisher Correction: DOR activation in mature oligodendrocytes regulates α-ketoglutarate metabolism leading to enhanced remyelination in aged mice

by Clinical Neuropsychologist | Tuesday, September 24, 2024 | Neuroscience

Nature Neuroscience, Published online: 24 September 2024; doi:10.1038/s41593-024-01785-2Publisher Correction: DOR activation in mature oligodendrocytes regulates α-ketoglutarate metabolism leading to enhanced remyelination in aged mice If you do not see content above,...