Microglia as hunters or gatherers of brain synapses

by Clinical Neuropsychologist | Wednesday, December 11, 2024 | Neuroscience

Nature Neuroscience, Published online: 11 December 2024; doi:10.1038/s41593-024-01818-wHow microglia sculpt brain circuits is not clear. Here, the authors propose that their contribution to synapse removal may occur by severing synapses (culling) or collecting...

Stepwise molecular specification of excitatory synapse diversity onto cerebellar Purkinje cells

by Clinical Neuropsychologist | Tuesday, December 10, 2024 | Neuroscience

Nature Neuroscience, Published online: 10 December 2024; doi:10.1038/s41593-024-01826-wBrain function requires the formation of diverse and specific synapses. The authors show that the molecular code specifying excitatory connectivity on Purkinje cells evolves in an...

Dissociable control of motivation and reinforcement by distinct ventral striatal dopamine receptors

by Clinical Neuropsychologist | Monday, December 9, 2024 | Neuroscience

Nature Neuroscience, Published online: 09 December 2024; doi:10.1038/s41593-024-01819-9Ventral striatal dopamine D3 and D1 receptors regulate motivation and reinforcement, respectively, through dissociable physiological actions. If you do not see content above, kindly...

Thermally induced neuronal plasticity in the hypothalamus mediates heat tolerance

by Clinical Neuropsychologist | Monday, December 9, 2024 | Neuroscience

Nature Neuroscience, Published online: 09 December 2024; doi:10.1038/s41593-024-01830-0Ambroziak, Nencini, Pohle and colleagues identify a slowly emerging plasticity mechanism in a discrete set of hypothalamic preoptic neurons that is triggered by long-term heat...

Motivating interest in D3 dopamine receptors

by Clinical Neuropsychologist | Monday, December 9, 2024 | Neuroscience

Nature Neuroscience, Published online: 09 December 2024; doi:10.1038/s41593-024-01820-2Reward signaling via dopamine is most commonly thought of as acting through neurons expressing either D1 or D2 dopamine receptors. Enriquez-Traba et al. show that neurons in the...

Author Correction: Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction

by Clinical Neuropsychologist | Friday, December 6, 2024 | Neuroscience

Nature Neuroscience, Published online: 06 December 2024; doi:10.1038/s41593-024-01853-7Author Correction: Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction If you do not see content above,...