Integrating multimodal data to understand cortical circuit architecture and function

by Clinical Neuropsychologist | Monday, March 24, 2025 | Neuroscience

Nature Neuroscience, Published online: 24 March 2025; doi:10.1038/s41593-025-01904-7This paper discusses how experimental and computational studies integrating multimodal data, such as RNA expression, connectivity and neural activity, are advancing our understanding...

Phase of firing does not reflect temporal order in sequence memory of humans and recurrent neural networks

by Clinical Neuropsychologist | Monday, March 24, 2025 | Neuroscience

Nature Neuroscience, Published online: 24 March 2025; doi:10.1038/s41593-025-01893-7The temporal order of events in working memory is thought to be reflected by ordered neuronal firing at different phases. Here the authors show that this is not the case and that phase...

Author Correction: Mitochondrial respiratory complex IV deficiency recapitulates amyotrophic lateral sclerosis

by Clinical Neuropsychologist | Friday, March 21, 2025 | Neuroscience

Nature Neuroscience, Published online: 21 March 2025; doi:10.1038/s41593-025-01941-2Author Correction: Mitochondrial respiratory complex IV deficiency recapitulates amyotrophic lateral sclerosis If you do not see content above, kindly GO TO SOURCE. Not all publishers...

Synaptic plasticity rules driving representational shifting in the hippocampus

by Clinical Neuropsychologist | Thursday, March 20, 2025 | Neuroscience

Nature Neuroscience, Published online: 20 March 2025; doi:10.1038/s41593-025-01894-6Madar et al. report that behavioral timescale synaptic plasticity (BTSP), not spike-timing-dependent plasticity, explains heterogeneous place fields shifting in the hippocampus. The...

Cancer research needs neuroscience and neuroscientists

by Clinical Neuropsychologist | Thursday, March 20, 2025 | Neuroscience

Nature Neuroscience, Published online: 20 March 2025; doi:10.1038/s41593-025-01925-2The nervous system can drive the initiation, growth, spread, and therapy resistance of cancer, and cancer can manipulate the nervous system in ways that further support disease...

Prospective contingency explains behavior and dopamine signals during associative learning

by Clinical Neuropsychologist | Tuesday, March 18, 2025 | Neuroscience

Nature Neuroscience, Published online: 18 March 2025; doi:10.1038/s41593-025-01915-4The authors show that behavior and dopamine responses track prospective, but not retrospective, contingency. These results are explained by temporal difference (TD) learning models,...