State-dependent signal flow hierarchy in the human cerebral cortex

by Clinical Neuropsychologist Online | Tuesday, September 1, 2026 | Neuroscience

Nature Neuroscience, Published online: 01 September 2026; doi:10.1038/s41593-026-02389-8A unified imaging framework integrates effective connectivity algorithms, revealing state-dependent functional hierarchies in the human brain. Simulations and empirical validation...

Borrowing from Improv to Decode Language in Everyday Conversation 

by Clinical Neuropsychologist Online | Monday, August 31, 2026 | Neuroscience

For people who know Caitriona Douglas, it came as no surprise that she decided to pursue research that does fine-grained analysis of conversations.  “I grew up in a bilingual environment and had childhood speech and language disorders,” Douglas recalls. “For me, a...

Spatial mapping of RNA turnover kinetics in the mouse brain

by Clinical Neuropsychologist Online | Monday, August 31, 2026 | Neuroscience

Nature Neuroscience, Published online: 31 August 2026; doi:10.1038/s41593-026-02420-yThe authors developed spatial NT-seq to map the landscape of RNA turnover and stability regulation in the mouse brain, identifying the dentate gyrus as a turnover hotspot and...

Social isolation recruits amygdala–medial prefrontal cortex projections to escalate alcohol drinking in male mice

by Clinical Neuropsychologist Online | Tuesday, August 25, 2026 | Neuroscience

Nature Neuroscience, Published online: 25 August 2026; doi:10.1038/s41593-026-02413-xSocial isolation recruits a basolateral amygdala–medial prefrontal cortex circuit to escalate alcohol drinking in male mice. This pathway reshapes prefrontal population dynamics,...

Motor neurons organize Drosophila feeding sequences via a disinhibitory cascade

by Clinical Neuropsychologist Online | Monday, August 24, 2026 | Neuroscience

Nature Neuroscience, Published online: 24 August 2026; doi:10.1038/s41593-026-02412-ySui, Yi, Zhou and colleagues show that motor neurons actively orchestrate Drosophila feeding sequences through a feedforward disinhibition cascade. In coordinating their own activity,...

Roles of autophagy in brain homeostasis and disease

by Clinical Neuropsychologist Online | Monday, August 24, 2026 | Neuroscience

Nature Neuroscience, Published online: 24 August 2026; doi:10.1038/s41593-026-02426-6Autophagy, a quality-control pathway for protein and organelle degradation, is indispensable to CNS cells, with impairments in autophagy linking it to a spectrum of disorders—from...