Abstract
INTRODUCTION
Alzheimer’s disease (AD) disproportionately affects minoritized populations who remain underrepresented in AD trials.
METHODS
We partnered with local nursing community-based organizations to implement a culturally tailored educational intervention and recruit Hispanic/Latino American, Filipino American, and Korean American adults aged 55 to 80 for the AHEAD study, a preclinical AD trial, at the University of California, Irvine.
RESULTS
We engaged 654 individuals across 21 events, leading to 71 prescreenings: 21.1% Filipino, 11.2% Hispanic/Latino, and 67.6% Korean adults. Ineligibility due to age and language barriers was common among Hispanic/Latino and Korean adults, respectively. Filipino adults often withdrew interest or were lost to follow-up. Ultimately, 25 participants enrolled: eight Filipino, two Hispanic/Latino, and 15 Korean adults. Tailored, culturally relevant content significantly contributed to the engagement success.
DISCUSSION
This study demonstrates the value and impact of novel partnerships with health-related provider organizations that provide trusted care and access to underrepresented communities.
Highlights
Six hundred and fifty four underrepresented individuals were reached, and 25 enrolled in the AHEAD 3-45 trial.
Twenty-one community events were held via partnerships with nursing and community organizations.
The study engaged 21% Filipino, 11% Hispanic/Latino, 68% Korean adults.
Community-Based Participatory Research (CBPR) principles enhanced the recruitment process.
Transparent communication and joint planning were key.
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This post is Copyright: Christian R. Salazar,
Melanie Tallakson,
Maria G. Corona,
Edwin Duran,
Eunji Russ,
Dan Hoang,
Romina A. Romero,
David L. Sultzer,
Joshua D. Grill,
Hye‐Won Shin | August 30, 2024