Evidence is limited on the role of mid-life Dietary Approaches to Stop Hypertension (DASH) diet in late-life subjective cognitive complaints (SCCs).
We included 5116 women (mean age in 1985–1991: 46 years) from the New York University Women’s Health Study. SCCs were assessed from 2018 to 2020 (mean age: 79 years) by a 6-item questionnaire.
Compared to women in the bottom quartile of the DASH scores, the odds ratio (OR) for having two or more SCCs was 0.83 (95% confidence interval: 0.70–0.99) for women in the top quartile of DASH scores at baseline (P for trend = 0.019). The association was similar with multiple imputation and inverse probability weighting to account for potential selection bias. The inverse association was stronger in women without a history of cancer (P for interaction = 0.003).
Greater adherence to the DASH diet in mid-life was associated with lower prevalence of late-life SCCs in women.

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This post is Copyright: Yixiao Song,
Fen Wu,
Sneha Sharma,
Tess V. Clendenen,
Sandra India‐Aldana,
Yelena Afanasyeva,
Yian Gu,
Karen L. Koenig,
Anne Zeleniuch‐Jacquotte,
Yu Chen | February 22, 2024

Wiley: Alzheimer’s & Dementia: Table of Contents