Abstract
INTRODUCTION
Geographic variation in diagnosed cases of Alzheimer’s disease and related dementias (ADRD) could be due to underlying population risk or differences in intensity of new case identification. Areas with low ADRD diagnostic intensity could be targeted for additional surveillance efforts.
METHODS
Medicare claims were used for a cohort of older adults across hospital referral regions (HRRs). ADRD-specific regional diagnosis intensity was measured as the ratio of expected new ADRD cases (estimated using population demographics, risk factors, and practice intensity) compared to observed ADRD-diagnosed cases.
RESULTS
Crude new ADRD diagnosis rate ranged from 1.7 to 5.4 per 100 across HRRs. ADRD-specific diagnosis intensity ranged from 0.69 to 1.47 and varied most for Black, Hispanic, and the youngest (66–74) subgroups. Across all subgroups, ADRD diagnosis intensity was associated with 2-fold difference in receiving an ADRD diagnosis.
DISCUSSION
Where one resides influences the likelihood of receiving an ADRD diagnosis, particularly among those 66–74 years of age and minoritized groups.
Highlights

Rate of new Alzheimer’s disease and related dementias (ADRD) case identification varies geographically across the United States.
Variation in case identification is greatest in Black, Hispanic, and young-old groups.
Intensity of diagnosis (ie, case identification) unrelated to population risk differs across place.
Likelihood of receiving an ADRD diagnosis varies 2-fold based on place of residence.


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This post is Copyright: Julie P. W. Bynum,
Slim Benloucif,
Jonathan Martindale,
A. James O’Malley,
Matthew A. Davis | August 16, 2024

Wiley: Alzheimer’s & Dementia: Table of Contents