Age-related sensory and motor impairment are associated with risk of dementia. No study has examined the joint associations of multiple sensory and motor measures on prevalence of early cognitive impairment (ECI).
Six hundred fifty participants in the Baltimore Longitudinal Study of Aging completed sensory and motor function tests. The association between sensory and motor function and ECI was examined using structural equation modeling with three latent factors corresponding to multisensory, fine motor, and gross motor function.
The multisensory, fine, and gross motor factors were all correlated (r = 0.74 to 0.81). The odds of ECI were lower for each additional unit improvement in the multisensory (32%), fine motor (30%), and gross motor factors (12%).
The relationship between sensory and motor impairment and emerging cognitive impairment may guide future intervention studies aimed at preventing and/or treating ECI.

Sensorimotor function and early cognitive impairment (ECI) prevalence were assessed via structural equation modeling.
The degree of fine and gross motor function is associated with indicators of ECI.
The degree of multisensory impairment is also associated with indicators of ECI.

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This post is Copyright: Zahra N. Sayyid,
Hang Wang,
Yurun Cai,
Alden L. Gross,
Bonnielin K. Swenor,
Jennifer A. Deal,
Frank R. Lin,
Amal A. Wanigatunga,
Ryan J. Dougherty,
Qu Tian,
Eleanor M. Simonsick,
Luigi Ferrucci,
Jennifer A. Schrack,
Susan M. Resnick,
Yuri Agrawal | February 20, 2024

Wiley: Alzheimer’s & Dementia: Table of Contents