Abstract
INTRODUCTION
It is important to understand the socioeconomic and medical determinants of subjective cognitive decline (SCD) at a population level in the United States.
METHODS
The primary outcomes are state-level rates of SCD and SCD-related functional impairment in adults aged ≥ 45, both measured in the Behavioral Risk Factor Surveillance System from 2016 to 2022. The exposures are state-level rates of poverty, unemployment, homelessness, college education, racial and ethnic minorities, uninsurance, smoking, hypertension, diabetes, and obesity as well as household income and physician density.
RESULTS
The strongest state-level associations with rates of SCD were the prevalence of diabetes (rho = 0.64), hypertension (rho = 0.59), and poverty (rho = 0.58; all p < 0.001), and with SCD-related functional impairment were prevalence of poverty (rho = 0.71), diabetes (rho = 0.68), and hypertension (rho = 0.53; all p < 0.001).
DISCUSSION
This study highlights critical links between SCD and socioeconomic and medical determinants in adults aged ≥ 45 in the United States, including the prevalence of poverty, diabetes, and hypertension.
Highlights
State-level analysis reveals socioeconomic and medical risk factors for subjective cognitive decline (SCD) at a population level.
The prevalence of poverty is a critical contributor to the state-level prevalence of SCD.
The prevalence of diabetes and hypertension are also strong state-level determinants of SCD.
Addressing the burden of cognitive decline at the population level necessitates targeting socioeconomic and medical factors.
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This post is Copyright: Adam de Havenon,
Eric L. Stulberg,
Lauren Littig,
Ka‐Ho Wong,
Daniel Sarpong,
Vivian Li,
Richa Sharma,
Guido J. Falcone,
Jeff D. Williamson,
Nicholas M. Pajewski,
Rebecca F. Gottesman,
Adam M. Brickman,
Kevin N. Sheth | October 1, 2024