ABSTRACT
Background and Purpose
To determine the diagnostic accuracy of median nerve ultrasound in suspected cases of carpal tunnel syndrome (CTS) in a prospective, real-world study.
Methods
This prospective study was carried out over one year at Roy Neuro Care Centre, Ranchi, Jharkhand, India. The clinical, electrophysiologic, and ultrasonographic findings in suspected cases of CTS were collected. A history and physical examination consistent with CTS were considered the gold standard for diagnosis.
Results
A total of 134 patients with symptoms suggestive of CTS were enrolled, and both wrists were examined. The diagnostic accuracy of various ultrasound parameters including maximum cross-sectional area (CSA) of the median nerve in the tunnel, difference between CSA at the level of the pronator quadratus compared to the carpal tunnel, and wrist-to-forearm ratio were evaluated by individual, parallel, and serial testing strategies using optimal cut-off values determined by the Youden Index. Parallel testing provided the highest sensitivity, making it suitable for screening, whereas serial testing produced the highest overall accuracy.
Conclusion
Median nerve ultrasound is an accurate diagnostic tool for CTS in a real-world setting.
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This post is Copyright: Ujjawal Roy,
Michael S. Cartwright,
Achal Kumar Srivastava,
Abhishek Dixit,
Ajay Panwar,
Meenakshi Vanchi,
Guhan Ramamurthy,
M. M. Arun Shivaraman,
Saankritya Ayan,
Saket Verma,
Prabhat Kumar Lal | November 4, 2025
Wiley: Journal of Neuroimaging: Table of Contents