Nature Neuroscience, Published online: 15 April 2026; doi:10.1038/s41593-026-02261-9This study uncovers how amyloid-β boosts astrocyte calcium activity, increasing cholesterol and disrupting brain waste clearance in an Alzheimer’s disease mouse model. Targeting astrocyte calcium or cholesterol restores clearance and improves cognition.
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This post is Copyright: | April 15, 2026
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