Nature Neuroscience, Published online: 21 November 2025; doi:10.1038/s41593-025-02115-wAstrocytes are associated with Alzheimer’s disease pathogenesis. We found that the transcription factor Sox9 functions to enhance astrocytic phagocytosis of Aβ plaques via MEGF10, and this clearance of plaques is associated with the preservation of cognitive function in mouse models.
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This post is Copyright: | November 21, 2025
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