Nature Neuroscience, Published online: 18 December 2025; doi:10.1038/s41593-025-02154-3This study reveals how distal DNA ‘switches’ control gene activity in human astrocytes. Using CRISPRi screens and single-cell RNA-seq, we map enhancer–gene links, highlight Alzheimer’s disease-related targets and introduce a model that predicts additional regulatory interactions.
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This post is Copyright: | December 18, 2025
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