Nature Neuroscience, Published online: 25 June 2024; doi:10.1038/s41593-024-01653-zWe present a developmental atlas that offers insight into sequential epigenetic changes underlying early human brain development modeled in organoids, which reconstructs the differentiation trajectories of all major CNS regions. It shows that epigenetic regulation via the installation of activating histone marks precedes activation of groups of neuronal genes.

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This post is Copyright: | June 25, 2024
Nature Neuroscience