Nature Neuroscience, Published online: 14 March 2025; doi:10.1038/s41593-025-01914-5Targeting the endothelium across ages and neurodegenerative diseases in 92 donors with single-cell inCITE-seq reveals similar alterations in ~40% of capillaries in AD, ALS and FTD. Endothelial TDP-43 loss coincides with increased nuclear p65/NF-κB activity and reduced Wnt/β-catenin.
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This post is Copyright: Omar M. F. Omar | March 14, 2025
Nature Neuroscience