Nature Neuroscience, Published online: 19 December 2025; doi:10.1038/s41593-025-02145-4We explored how external conditions shape cognitive function. Classical olfactory learning assays revealed that Caenorhabditis elegans kept on ice or treated with lithium exhibited delayed forgetting of olfactory memories. We showed that the worm’s cold-tolerance internal state ‘switch’ and diacylglycerol (DAG) pathway activity in AWC neurons regulate memory retention.
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This post is Copyright: | December 19, 2025
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