Nature Neuroscience, Published online: 27 May 2025; doi:10.1038/s41593-025-01979-2The microglia–neuron interactions contributing to neuronal hyperexcitability are unclear. Here, the authors show how GABA and C3 signaling coordinate microglial engulfment of inhibitory synapses, driving excitatory–inhibitory imbalance and neuronal hyperexcitability in epilepsy.
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This post is Copyright: | May 27, 2025
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