Nature Neuroscience, Published online: 11 March 2024; doi:10.1038/s41593-024-01606-6Cold sensor identities in peripheral somatosensory neurons remain obscure. We show that GluK2, a kainate-type glutamate-sensing chemoreceptor that mediates synaptic transmission in the brain, mediates the sensing of cold but not cool temperatures in mouse dorsal root ganglia neurons in the periphery. Thus, we identify GluK2 as a cold-sensing thermoreceptor.

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This post is Copyright: | March 11, 2024
Nature Neuroscience