Nature Neuroscience, Published online: 26 May 2026; doi:10.1038/s41593-026-02317-wIn PS19 mice, microglia-derived glycoprotein nonmetastatic melanoma protein B promotes mitochondrial extracellular vesicle secretion, enabling mitochondrial transfer to astrocytes. This improves astrocytic function and reduces Alzheimer’s disease (AD) symptoms, while GPNMB deficiency impairs it, highlighting new AD treatment avenues.
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This post is Copyright: | May 26, 2026
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