Nature Neuroscience, Published online: 10 March 2026; doi:10.1038/s41593-026-02234-ySu et al. show that inflammatory arthritis pain stems from sustained interferon-driven MNK1/MNK2–elF4E signaling that sensitizes joint-innervating neurons. Blocking this pathway reverses pain, suggesting a targeted therapeutic strategy.
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This post is Copyright: | March 10, 2026
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