Nature Neuroscience, Published online: 29 February 2024; doi:10.1038/s41593-024-01589-4C9orf72 ALS/FTD polyGR and polyPR knock-in mice show cortical hyperexcitability and motor neuron loss accompanied by an increase in extracellular matrix proteins in the spinal cord that is conserved in patient iPS cell-derived neurons and is neuroprotective.

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This post is Copyright: Carmelo Milioto | February 29, 2024
Nature Neuroscience