Nature Neuroscience, Published online: 24 February 2025; doi:10.1038/s41593-024-01865-3The authors show PTEN mutations, which can cause both congenital hydrocephalus and autism spectrum disorder, disrupt CSF homeostasis and brain connectivity in mice. Reducing mTORC1 activation ameliorates ventricular enlargement and neuronal deficits.
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This post is Copyright: Tyrone DeSpenza Jr. | February 24, 2025
Nature Neuroscience