Nature Neuroscience, Published online: 18 March 2026; doi:10.1038/s41593-026-02237-9Zhou, Ho and colleagues show that, in mice, a schizophrenia-associated mutation impairs belief updating by weakening mediodorsal (MD) thalamus activity. Boosting this activity restored flexible decision-making, suggesting MD thalamus as a potential therapeutic target.


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This post is Copyright: | March 18, 2026
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