Nature Neuroscience, Published online: 31 October 2025; doi:10.1038/s41593-025-02096-wTDP-43 dysfunction in ALS/FTD causes faulty splicing of the KCNQ2 ion channel, leading to toxic protein buildup, neuron hyperactivity and a potential new biomarker and treatment target using RNA-based therapies.


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This post is Copyright: | October 31, 2025
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