Nature Neuroscience, Published online: 24 November 2025; doi:10.1038/s41593-025-02125-8Lecanemab, a leading therapy for Alzheimer’s disease, induces an Fc-mediated transcriptional program in human microglia, linked to osteopontin and enhanced plaque phagocytosis, suggesting alternative strategies to promote plaque clearance.
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This post is Copyright: | November 24, 2025
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