by Clinical Neuropsychologist Online | Monday, September 28, 2026 | Dementia
Abstract INTRODUCTION Exposure to aerosolized pollutants is a risk factor for cognitive impairment and dementia, but the specific features of exposure-related neurodegeneration remain unclear. METHODS We measured the World Trade Center Neurotoxicant Exposure Severity...
by Clinical Neuropsychologist Online | Monday, September 28, 2026 | Dementia
Abstract INTRODUCTION We tested whether combining Alzheimer’s disease and related dementias (ADRD) polygenic risk scores (PRS) with biological aging markers improves ADRD risk prediction. METHODS In 16,215 UK Biobank (UKB) participants free of ADRD at baseline...
by Clinical Neuropsychologist Online | Monday, September 28, 2026 | Dementia
Abstract INTRODUCTION Residential greenspace is linked to mental and cardiometabolic health, but longitudinal studies on detailed greenspace and dementia incidence are limited. METHODS We followed 2993 dementia-free participants in the Swedish National Study on Aging...
by Clinical Neuropsychologist Online | Thursday, September 24, 2026 | Dementia
Abstract INTRODUCTION Microglia-mediated clearance of amyloid beta (Aβ) is crucial for mitigating Alzheimer’s disease (AD) progression, yet the molecular regulators of microglial phagocytosis remain incompletely understood. METHODS We assessed AD-related...
by Clinical Neuropsychologist Online | Thursday, September 24, 2026 | Dementia
Abstract INTRODUCTION Cognitive changes in the asymptomatic stages of Alzheimer disease (AD) are subtle and difficult to detect using conventional cognitive tests. High-frequency smartphone-based testing may improve sensitivity to these changes, but generational...