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Current status of professional memory clinics, inpatient services, and health professionals in China

by Clinical Neuropsychologist Online | Thursday, September 26, 2024 | Dementia

Abstract INTRODUCTION This study aims to explore the current status of dementia-specific diagnosis and treatment in China. METHODS This national survey was conducted in mainland China from September 2022 to February 2023, with strong support from the Cognitive...

Self‐reported hearing loss is associated with faster cognitive and functional decline but not diagnostic conversion in the ADNI cohort

by Clinical Neuropsychologist Online | Thursday, September 26, 2024 | Dementia

Abstract INTRODUCTION Hearing loss is identified as one of the largest modifiable risk factors for cognitive impairment and dementia. Studies evaluating this relationship have yielded mixed results. METHODS We investigated the longitudinal relationship between...

Longitudinal associations between exercise and biomarkers in autosomal dominant Alzheimer’s disease

by Clinical Neuropsychologist Online | Thursday, September 26, 2024 | Dementia

Abstract INTRODUCTION We investigated longitudinal associations between self-reported exercise and Alzheimer’s disease (AD)-related biomarkers in individuals with autosomal dominant AD (ADAD) mutations. METHODS Participants were 308 ADAD mutation carriers aged...

Effectiveness of electro‐acupuncture for cognitive improvement on Alzheimer’s disease quantified via PET imaging of sphingosine‐1‐phosphate receptor 1

by Clinical Neuropsychologist Online | Wednesday, September 25, 2024 | Dementia

Abstract INTRODUCTION Electro-acupuncture (EA) has demonstrated potential in improving mild-to-moderate dementia in clinics, but the underlying scientific target remains unclear. METHODS EA was administered to APP/PS1 Alzheimer’s disease (AD) mice, with...

MEDI1814 selectively reduces free Aβ42 in cerebrospinal fluid of non‐clinical species and Alzheimer’s disease patients

by Clinical Neuropsychologist Online | Wednesday, September 25, 2024 | Dementia

Abstract INTRODUCTION Small molecules and antibodies are being developed to lower amyloid beta (Aβ) peptides. METHODS We describe MEDI1814, a fully human high-affinity monoclonal antibody selective for Aβ42, the pathogenic self-aggregating species of Aβ. RESULTS...
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