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Empowering a person‐centered long‐term care workforce

by Clinical Neuropsychologist | Thursday, July 18, 2024 | Dementia

Abstract Currently there is a crisis in the long-term care workforce, as many workers experience poor pay, a lack of training, burnout, low quality working conditions, and physical strain, which is leading to a workforce shortage. To address this, the...

Genome‐wide meta‐analysis identifies ancestry‐specific loci for Alzheimer’s disease

by Clinical Neuropsychologist | Thursday, July 18, 2024 | Dementia

Abstract INTRODUCTION Alzheimer’s disease (AD) is a devastating neurological disease with complex genetic etiology. Yet most known loci have only identified from the late-onset type AD in populations of European ancestry. METHODS We performed a two-stage...

Sustained frailty remission and dementia risk in older adults: A longitudinal study

by Clinical Neuropsychologist | Wednesday, July 17, 2024 | Dementia

Abstract INTRODUCTION Physical frailty is reversible, but little is known about the sustainability of frailty remission and its impact on dementia. METHODS Data were derived from the National Health and Aging Trends Study (NHATS) (2011 to 2021). Physical frailty was...

The Bayesian approach for real‐world implementation of plasma p‐tau217 in tertiary care memory clinics in Thailand

by Clinical Neuropsychologist | Wednesday, July 17, 2024 | Dementia

Abstract INTRODUCTION Plasma phosphorylated tau (p-tau)217 is a promising biomarker for Alzheimer’s disease (AD) diagnosis, but its clinical implementation remains challenging. We propose a strategy based on Bayes’ theorem and test it in real-life memory...

Care partner‐informed meaningful change thresholds for the Clinical Dementia Rating‐Sum of Boxes for trials of early Alzheimer’s disease

by Clinical Neuropsychologist | Wednesday, July 17, 2024 | Dementia

Abstract INTRODUCTION Consensus definitions of meaningful within-patient change (MWPC) on the Clinical Dementia Rating-Sum of Boxes (CDR-SB) are needed. Existing estimates use clinician-rated anchors in clinically diagnosed Alzheimer’s disease (AD) populations....
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