by Clinical Neuropsychologist | Tuesday, June 25, 2024 | Dementia
Abstract INTRODUCTION The established cerebrospinal fluid (CSF) phosphorylated tau181 (p-tau181) may not reliably reflect concomitant Alzheimer’s disease (AD) and primary age-related tauopathy (PART) found in Creutzfeldt–Jakob disease (CJD) at autopsy. METHODS...
by Clinical Neuropsychologist | Monday, June 24, 2024 | Dementia
Alzheimer’s &Dementia, EarlyView. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: | June 24, 2024 Wiley: Alzheimer’s & Dementia: Table...
by Clinical Neuropsychologist | Saturday, June 22, 2024 | Dementia
Abstract INTRODUCTION The recent introduction of seed amplification assays (SAAs) detecting misfolded α-synuclein, a pathology-specific marker for Lewy body disease (LBD), has allowed the in vivo identification and phenotypic characterization of patients with...
by Clinical Neuropsychologist | Saturday, June 22, 2024 | Dementia
Abstract The under-representation of non-European cohorts in neurodegenerative disease genome-wide association studies (GWAS) hampers precision medicine efforts. Despite the inherent genetic and phenotypic diversity in these diseases, GWAS research consistently...
by Clinical Neuropsychologist | Saturday, June 22, 2024 | Dementia
Abstract INTRODUCTION We examined whether the aging suppressor KLOTHO gene’s functionally advantageous KL-VS variant (KL-VS heterozygosity [KL-VSHET]) confers resilience against deleterious effects of aging indexed by cerebrospinal fluid (CSF) biomarkers of...
