by Clinical Neuropsychologist Online | Tuesday, September 10, 2024 | Dementia
Abstract INTRODUCTION Frontotemporal dementia (FTD) is characterized by phenotypic and genetic heterogeneities. However, reports on the large Chinese FTD cohort are lacking. METHODS Two hundred forty-eight patients with FTD were enrolled. All patients and 2010 healthy...
by Clinical Neuropsychologist Online | Tuesday, September 10, 2024 | Dementia
Abstract INTRODUCTION Few studies have examined the relationship between education and cognition among the oldest–old. METHODS Cognitive assessments were conducted biannually for 803 participants (62.6% women) of LifeAfter90, a longitudinal study of individuals ≥ 90...
by Clinical Neuropsychologist Online | Tuesday, September 10, 2024 | Dementia
Abstract INTRODUCTION We investigated distinctive factors associated with cognitive reserve (CR) based on education level. METHODS Among 1247 participants who underwent neuropsychological assessment, amyloid positron emission tomography, and brain magnetic resonance...
by Clinical Neuropsychologist Online | Tuesday, September 10, 2024 | Dementia
Abstract INTRODUCTION We investigated the interactive associations between amyloid and hypertension on the entorhinal cortex (EC) tau and atrophy and the role of cerebral blood flow (CBF) as a shared mechanism by which amyloid and hypertension contribute to EC tau and...
by Clinical Neuropsychologist Online | Tuesday, September 10, 2024 | Dementia
Abstract INTRODUCTION Magnetic resonance imaging (MRI) segmentation algorithms make it possible to study detailed medial temporal lobe (MTL) substructures as hippocampal subfields and amygdala subnuclei, offering opportunities to develop biomarkers for preclinical...
