by Clinical Neuropsychologist Online | Monday, July 29, 2024 | Dementia
Abstract INTRODUCTION Altered neurometabolism, detectable via proton magnetic resonance spectroscopic imaging (1H-MRSI), is spatially heterogeneous and underpins cognitive impairments in Alzheimer’s disease (AD). However, the spatial relationships between...
by Clinical Neuropsychologist Online | Monday, July 29, 2024 | Dementia
Abstract INTRODUCTION We investigate the role of osteopontin (OPN) in participants with Pre-symptomatic Alzheimer’s disease (AD), mild cognitive impairment (MCI), and in AD brains. METHODS Cerebrospinal fluid (CSF) OPN, AD, and synaptic biomarker levels were...
by Clinical Neuropsychologist Online | Monday, July 29, 2024 | Dementia
Abstract BACKGROUND Alzheimer’s disease (AD) is a neurodegenerative condition characterized by cognitive decline. To date, the specific dysfunction in the brain’s hierarchical structure in AD remains unclear. METHODS We introduced the structural decoupling...
by Clinical Neuropsychologist Online | Monday, July 29, 2024 | Dementia
Dementia, Volume 23, Issue 8, Page 1416-1418, November 2024. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: Lily Haopu Ren | July 29, 2024 SAGE...
by Clinical Neuropsychologist Online | Sunday, July 28, 2024 | Dementia
Abstract INTRODUCTION This study investigates primary lateral sclerosis (PLS) as a rare manifestation of the presenilin 1 (PSEN1) NM_000021 c.851C > T p.Pro284Leu variant in three siblings of a Colombian family, outlining its clinical and neuropathological features...
