by Clinical Neuropsychologist | Thursday, June 13, 2024 | Dementia
Abstract BACKGROUND Mild cognitive impairment (MCI) heightens Alzheimer’s disease (AD) risk, with diabetes mellitus (DM) potentially exacerbating this vulnerability. This study identifies the optimal intervention period and neurobiological targets in MCI to AD...
by Clinical Neuropsychologist | Wednesday, June 12, 2024 | Dementia
Abstract INTRODUCTION Brain-derived extracellular vesicles (BEVs) in blood allows for minimally-invasive investigations of central nervous system (CNS) -specific markers of age-related neurodegenerative diseases (NDDs). Polymer-based EV- and immunoprecipitation...
by Clinical Neuropsychologist | Tuesday, June 11, 2024 | Dementia
Abstract INTRODUCTION The cognitive impairment patterns and the association with Alzheimer’s disease (AD) in mental disorders remain poorly understood. METHODS We analyzed data from 486,297 UK Biobank participants, categorizing them by mental disorder history to...
by Clinical Neuropsychologist | Tuesday, June 11, 2024 | Dementia
Abstract INTRODUCTION Female-specific reproductive factors and exogeneous estrogen use are associated with cognition in later life. However, the underlying mechanisms are not understood. The present study aimed to investigate the effect of reproductive factors on...
by Clinical Neuropsychologist | Tuesday, June 11, 2024 | Dementia
Abstract INTRODUCTION Most people with Alzheimer’s disease and related dementia (ADRD) also suffer from two or more chronic conditions, known as multiple chronic conditions (MCC). While many studies have investigated the MCC patterns, few studies have considered...
