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Correlations between plasma markers and brain Aβ deposition across the AD continuum: Evidence from SILCODE

by Clinical Neuropsychologist Online | Wednesday, July 10, 2024 | Dementia

Abstract BACKGROUND Previous studies have found that Alzheimer’s disease (AD)-related plasma markers are associated with amyloid beta (Aβ) deposition, but the change of this association in different Aβ pathological stages remains unclear. METHODS Data were...

Clinical recognition of frontotemporal dementia with right anterior temporal predominance: A multicenter retrospective cohort study

by Clinical Neuropsychologist Online | Wednesday, July 10, 2024 | Dementia

Abstract INTRODUCTION Although frontotemporal dementia (FTD) with right anterior temporal lobe (RATL) predominance has been recognized, a uniform description of the syndrome is still missing. This multicenter study aims to establish a cohesive clinical phenotype....

Cardiometabolic multimorbidity, peripheral biomarkers, and dementia in rural older adults: The MIND‐China study

by Clinical Neuropsychologist Online | Wednesday, July 10, 2024 | Dementia

Abstract INTRODUCTION Evidence has emerged that cardiometabolic multimorbidity (CMM) is associated with dementia, but the underlying mechanisms are poorly understood. METHODS This population-based study included 5704 older adults. Of these, data were available in 1439...

Interplay between orthopedic interventions and dementia: Dementia risk after total knee replacement

by Clinical Neuropsychologist Online | Tuesday, July 9, 2024 | Dementia

Alzheimer’s &Dementia, EarlyView. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: Hui‐Chin Chang, Ru‐Yin Tsai, Chen‐Pi Li, Wen‐Chieh Liao,...

Early blood immune molecular alterations in cynomolgus monkeys with a PSEN1 mutation causing familial Alzheimer’s disease

by Clinical Neuropsychologist Online | Monday, July 8, 2024 | Dementia

Abstract INTRODUCTION More robust non-human primate models of Alzheimer’s disease (AD) will provide new opportunities to better understand the pathogenesis and progression of AD. METHODS We designed a CRISPR/Cas9 system to achieve precise genomic deletion of...
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