by Clinical Neuropsychologist Online | Wednesday, August 26, 2026 | Dementia
Abstract INTRODUCTION Few studies have examined the longitudinal associations between chronic stress, social support, and cognitive decline or whether sociodemographic factors modify associations. METHODS We included 3873 older adults enrolled in the Health and Aging...
by Clinical Neuropsychologist Online | Tuesday, August 25, 2026 | Dementia
Abstract BACKGROUND Polypharmacy, potentially inappropriate medications (PIMs), and drugs associated with drug-induced cognitive impairment (DICI) are highly prevalent in older adults and may affect cognitive decline. METHODS This observational retrospective study...
by Clinical Neuropsychologist Online | Tuesday, August 25, 2026 | Dementia
Abstract BACKGROUND Vascular and glymphatic dysfunction are increasingly implicated in Alzheimer’s disease (AD), particularly among apolipoprotein E (APOE) ε4 carriers. We investigated relationships among retinal microvasculature, glymphatic markers, and AD...
by Clinical Neuropsychologist Online | Tuesday, August 25, 2026 | Dementia
Abstract INTRODUCTION Cerebral amyloid angiopathy (CAA) is a leading cause of lobar intracerebral hemorrhage (ICH) in the elderly. The influence of apolipoprotein E (APOE) variants, CAA pathology, and concomitant Alzheimer’s disease (AD) neuropathologic changes...
by Clinical Neuropsychologist Online | Tuesday, August 25, 2026 | Dementia
Abstract INTRODUCTION Dementia is a public health challenge and exposures likely contribute to risk, though many have not been evaluated. We screened chemicals for enrichment with dementia genes and related pathways. METHODS We obtained gene lists from Agora and the...
