by Clinical Neuropsychologist Online | Thursday, May 23, 2024 | Dementia
Abstract INTRODUCTION Patients with subjective memory complaints (SMC) may include subgroups with different neuropsychological profiles and risks of cognitive impairment. METHODS Cluster analysis was performed on two datasets (n: 630 and 734) comprising demographic...
by Clinical Neuropsychologist Online | Thursday, May 23, 2024 | Dementia
Abstract INTRODUCTION We investigated the association of cognitive reserve (CR) with transitions across cognitive states and death. METHODS This population-based cohort study included 2631 participants (age ≥60 years) who were dementia-free at baseline and regularly...
by Clinical Neuropsychologist Online | Thursday, May 23, 2024 | Dementia
Abstract INTRODUCTION Tropomyosin related kinase B (TrkB) and C (TrkC) receptor signaling promotes synaptic plasticity and interacts with pathways affected by amyloid beta (Aβ) toxicity. Upregulating TrkB/C signaling could reduce Alzheimer’s disease (AD)-related...
by Clinical Neuropsychologist Online | Thursday, May 23, 2024 | Dementia
Cognitive screening measures are an established part of a dementia assessment and often include measures of subjective difficulties, e.g., Everyday Memory Questionnaire (EMQ), informant-rated difficulty, Cambridge Behavioural Inventory – Revised (CBI-R), and objective...
by Clinical Neuropsychologist Online | Thursday, May 23, 2024 | Dementia
Neurodegenerative diseases are a growing concern in an aging global population. Frailty, often conceptualized as a state of diminished physiological reserve and increased susceptibility to stressors, emerges as a pivotal factor in this context. While frailty may be...
