by Clinical Neuropsychologist Online | Tuesday, April 2, 2024 | Dementia
Abstract INTRODUCTION We conducted a rapid systematic review of minimal clinically important differences (MCIDs) for Alzheimer’s disease (AD) trial endpoints. METHODS Two reviewers searched EMBASE, MEDLINE, and PubMed from inception to June 4, 2023. RESULTS Ten...
by Clinical Neuropsychologist Online | Tuesday, April 2, 2024 | Dementia
Abstract INTRODUCTION There is limited knowledge about early-onset dementia (EOD) on fracture risk. METHODS Individuals ages 50 to 64 were identified from the National Database of Health Insurance Claims and Specific Health Checkups of Japan (2012 to 2019). The...
by Clinical Neuropsychologist Online | Monday, April 1, 2024 | Dementia
Abstract Alzheimer’s disease (AD) is a growing problem worldwide. Since ABCA7’s identification as a risk gene, it has been extensively researched for its role in the disease. We review its recently characterized structure and what the mechanistic insights teach...
by Clinical Neuropsychologist Online | Monday, April 1, 2024 | Dementia
Abstract INTRODUCTION Alternative splicing of the human MAPT gene generates six brain-specific TAU isoforms. Imbalances in the TAU isoform ratio can lead to neurodegenerative diseases, underscoring the need for precise control over TAU isoform balance. Tauopathies,...
by Clinical Neuropsychologist Online | Saturday, March 30, 2024 | Dementia
Alzheimer’s &Dementia, EarlyView. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: | March 30, 2024 Wiley: Alzheimer’s & Dementia: Table...
