by Clinical Neuropsychologist Online | Friday, March 15, 2024 | Dementia
Abstract INTRODUCTION Alzheimer’s Prevention Initiative Generation Study 1 evaluated amyloid beta (Aβ) active immunotherapy (vaccine) CAD106 and BACE-1 inhibitor umibecestat in cognitively unimpaired 60- to 75-year-old participants at genetic risk for...
by Clinical Neuropsychologist Online | Friday, March 15, 2024 | Dementia
Abstract INTRODUCTION The extent to which the Big Five personality traits and subjective well-being (SWB) are discriminatory predictors of clinical manifestation of dementia versus dementia-related neuropathology is unclear. METHODS Using data from eight independent...
by Clinical Neuropsychologist Online | Friday, March 15, 2024 | Dementia
Abstract INTRODUCTION To examine the burden and clusters of multimorbidity in association with mild cognitive impairment (MCI), dementia, and Alzheimer’s disease (AD)-related plasma biomarkers among older adults. METHODS This population-based study included 5432...
by Clinical Neuropsychologist Online | Friday, March 15, 2024 | Dementia
Abstract INTRODUCTION White matter hyperintensities (WMH) may promote clinical Alzheimer’s disease (AD) disparities between Black American (BA) and non-Hispanic White (nHW) populations. Using a novel measurement, unhealthy white matter connectivity (UWMC), we...
by Clinical Neuropsychologist Online | Thursday, March 14, 2024 | Dementia
Abstract INTRODUCTION Dementia risk may be elevated in socioeconomically disadvantaged neighborhoods. Reasons for this remain unclear, and this elevation has yet to be shown at a national population level. METHODS We tested whether dementia was more prevalent in...
