by Clinical Neuropsychologist Online | Wednesday, March 13, 2024 | Dementia
Abstract INTRODUCTION Depressive symptoms are associated with higher risk of dementia, but how they impact cognition in diverse populations is unclear. METHODS Asian, Black, Latino, or White participants (n = 2227) in the Kaiser Healthy Aging and Diverse Life...
by Clinical Neuropsychologist Online | Wednesday, March 13, 2024 | Dementia
Abstract INTRODUCTION We aimed to investigate the effect of apolipoprotein E4 (APOE) ε4 on synaptic density in cognitively impaired (CI) participants. METHODS One hundred ten CI participants underwent amyloid positron emission tomography (PET) with 18F-florbetapir and...
by Clinical Neuropsychologist Online | Wednesday, March 13, 2024 | Dementia
Abstract INTRODUCTION White matter hyperintensities (WMH) are associated with key dementia etiologies, in particular arteriolosclerosis and amyloid pathology. We aimed to identify WMH locations associated with vascular risk or cerebral amyloid-β1-42 (Aβ42)-positive...
by Clinical Neuropsychologist Online | Wednesday, March 13, 2024 | Dementia
Abstract INTRODUCTION Trials of effectiveness of treatment options for depression in dementia are an important priority. METHODS Randomized controlled trial to assess adapted Problem Adaptation Therapy (PATH) for depression in mild/moderate dementia caused by...
by Clinical Neuropsychologist Online | Wednesday, March 13, 2024 | Dementia
Abstract INTRODUCTION This review examines the concept of cognitive reserve (CR) in relation to brain aging, particularly in the context of dementia and its early stages. CR refers to an individual’s ability to maintain or regain cognitive function despite brain...
